Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a combined operation against an underground arms cache in Syrian territory used by the IS group, per a report from the UK's MoD.
The facility, identified by surveillance, was believed to be housing weapons and explosive materials, the statement said, and was situated in mountains just above the ancient city of Palmyra in central Syria.
"Our aircraft utilized precision-guided Paveway IV munitions to strike a number of approach shafts providing entry to the facility... initial indications suggest the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the operation late on Saturday and each participating jet made a safe return, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager refuelling tanker.
The Islamic State group - also known as the so-called Islamic State - imposed jihadist rule over significant areas in Syria and Iraq before its territorial defeat in 2019.
"This action shows British leadership, and commitment to operate in unison with our partners, to eradicate any resurgence of IS and their violent and radical beliefs in the area," the British Defence Secretary the minister stated.
RAF aircraft have conducted patrols over Syrian airspace to "forestall any attempted comeback" of the group after its military defeat at the battle of Baghuz in 2019, the authorities noted.
"I want to thank the personnel of our armed forces who took part in this mission for their professionalism and their bravery," the Defence Secretary commented. "They were among numerous UK service members on duty over Christmas and New Year. This operation, to eliminate militants who threaten our safety, highlights how our armed forces are always on standby, all year round, ensuring Britain's security within its borders and influential overseas."
During December, the United States armed forces executed what it called a "major assault" targeting Islamic State objectives in the country, following an attack resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The U.N. estimates Islamic State still maintains between 5,000 and 7,000 combatants in Iraq and Syria.